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Hi Calipsy,
I believe the two upgrades can be combined, but to be on the safe side I would upload them separately.
You will need the 2.0.10 to 2.012a patch, and the 2.0.12a to 2.0.13 patch. With both patches remove the install folder and any updated modules (such as newbb 2/CBB or news) or modules that you do not use, the system module is required so don't remove it. Then in both cases just upload the files to your server, no need to update the system module for these updates.
You should then have the latest 2.0.13 stable showing in the footer of your admin section and you are current (until the release of 2.2 final that is.)