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You'll need to edit mainfile.php to reflect the changes you have made to get it to work right.
// Physical path to the XOOPS documents (served) directory WITHOUT trailing slash
define( 'XOOPS_ROOT_PATH', 'rootpath/htdocs' );
// For forward compatibility
// Physical path to the XOOPS library directory WITHOUT trailing slash
define( 'XOOPS_PATH', 'rootpath/specialfolder/xoops_lib' );
// Physical path to the XOOPS datafiles (writable) directory WITHOUT trailing slash
define( 'XOOPS_VAR_PATH', 'rootpath/specialfolder/xoops_data' );
// Alias of XOOPS_PATH, for compatibility, temporary solution
define("XOOPS_TRUST_PATH", XOOPS_PATH);
// XOOPS Virtual Path (URL)
// Virtual path to your main XOOPS directory WITHOUT trailing slash
// Example: define( 'XOOPS_URL', 'http://somthingelse.com' );
define( 'XOOPS_URL', 'http://somthingelse.com' );