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Oi.
Let me give my also unqualified response.. I think Dave_L is right. You can customize your own site to do anything you'd like and not be forced to give your secrets to Tom, Dick or Harry. Doesn't matter if the site is on the internet or locked down to a secret cave somewhere.
You can go behind closed doors and develop and sell your own applications. How you use the free software is the only question. You can't modify someone else's work and claim it as your own to make money. Nearly all of the commercial applications are using some mix of Open Source software behind it.
Turn it around, the OS community won't be friendly toward freely helping to develop software that they can't freely use themselves. Charge $5.00 or $1,998.75 for your own creation that happens to run on top of OS apps like xoops, PHP, mySQL, Apache, etc.